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Methotrexate: Uses, Dosage, Side Effects - Drugs.com
Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.. Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung.It is also used to treat severe psoriasis and and certain forms of rheumatoid arthritis.

Methotrexate - Wikipedia
Methotrexate is an antimetabolite of the antifolate type. It is thought to affect cancer and rheumatoid arthritis by two different pathways. For cancer, methotrexate competitively inhibits dihydrofolate reductase (DHFR), an enzyme that participates in the tetrahydrofolate synthesis. The affinity of methotrexate for DHFR is about 1000-fold that of folate.

Methotrexate (Anti-Rheumatic) Oral : Uses, Side Effects ...
Methotrexate has rarely caused serious (sometimes fatal) side effects. Therefore, this medication should be used only to treat cancer or severe diseases caused by an overactive immune system (such ...

Methotrexate: MedlinePlus Drug Information
Methotrexate may cause very serious, life-threatening side effects. You should only take methotrexate to treat cancer or certain other conditions that are very severe and that cannot be treated with other medications.

Methotrexate (Trexall): Side Effects, Dosages, Treatment ...
Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole.. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia.

methotrexate (Rheumatrex): Side Effects & Dosage
Describes the medication methotrexate (Trexall, Rheumatrex) a drug used in treating certain diseases associated with abnormally rapid cell growth. Article includes descriptions, uses, drug interactions, and side effects.

Methotrexate Side Effects | RA Treatment
Methotrexate is one of the most effective and widely used medications for treating rheumatoid arthritis (RA) and other inflammatory types of arthritis. It’s also one of the safest arthritis drugs, insist rheumatologists, despite a common misconception among many patients and even some primary care ...

Methotrexate Injection: Side Effects, Dosage, Uses, and More
Methotrexate self-injectable solution is available as brand-name drugs. It’s not available in a generic form. Brand names: Rasuvo and Otrexup. Methotrexate comes in four forms: self-injectable ...

Methotrexate Side Effects in Detail - Drugs.com
Learn about the potential side effects of methotrexate. Includes common and rare side effects information for consumers and healthcare professionals.

Methotrexate for Rheumatoid Arthritis (RA) Treatment: How ...
Methotrexate is one of the most effective medications to treat rheumatoid arthritis (RA). It's the first drug most doctors prescribe after you’re diagnosed. It will help ease symptoms like joint ...

 

 

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* Latest Rheumatology News

       *** News Filter: "Methotrexate"

 

 

Diacerein for the Treatment of Rheumatoid Arthritis in Patients with Inadequate Response to Methotrexate: A Pilot Randomized, Double-blind, Placebo-controlled Add-on Trial  DocWire News

OBJECTIVE:To evaluate the efficacy and safety of diacerein in patients with rheumatoid arthritis (RA) who are methotrexate inadequate responders (MTX-IR).

Concomitant Methotrexate Has Little Effect on Clinical Outcomes of Abatacept in Rheumatoid Arthritis: A Propensity Score Matching Analysis  DocWire News

To compare the clinical outcomes of abatacept between rheumatoid arthritis patients with and without concomitant methotrexate treatment.

Eisai Enters Into Licensing Agreement With Medac Concerning Anti-Rheumatic Agent Methotrexate Subcutaneous Injection in Japan  BioSpace

Published: May 10, 2019. TOKYO, May 10, 2019 - (JCN Newswire) - Eisai Co., Ltd. announced today that it has entered into a license agreement with medac ...

Psoriatic Arthritis Remission Rates Increased With Golimumab Plus Methotrexate Therapy  Rheumatology Advisor

Early initiation of combination therapy with golimumab plus methotrexate doubled the number of patients achieving psoriatic arthritis remission compared with ...

Methotrexate Treatment in Rheumatoid Arthritis and Elevated Liver Enzymes: A Long-term Follow-up of Predictors, Surveillance, and Outcome in Clinical Practice  DocWire News

Predictors of alanine aminotransferase elevation in methotrexate treated rheumatoid arthritis patients, and to describe the monitoring of liver enzymes.

What is Causing This 30-Year-Old's Elevated CRP and Myalgia?  MedPage Today

Diagnostic odyssey leads to not-too-surprising conclusion.

Case Report: Stress Fractures in Systemic Lupus Erythematosus After Long-Term Methotrexate Use  Rheumatology Advisor

A case report published in Lupus demonstrated the negative effect of long-term use of methotrexate (MTX) on bone density, resulting in peculiar stress fractures ...

Case Highlights Gut Microbiome Alteration as Potential Treatment for PsA  Rheumatology Advisor

The outcome in this case is hypothesis-generating in that it suggests that the gut microbiome may play an etiologic role in psoriatic arthritis.

Updated 2019 ACR/AF Recommendations for Treating JIA Polyarthritis  Rheumatology Advisor

The American College of Rheumatology and Arthritis Foundation have released updated guidelines for management of non-systemic polyarthritis, sacroiliitis, ...

Juvenile Idiopathic Arthritis-Associated Uveitis: Updated 2019 Guidelines From ACR/AF  Rheumatology Advisor

The American College of Rheumatology and the Arthritis Foundation have released updated recommendations for the screening, monitoring, and treatment of ...

 

 

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