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            * Rheumatology101 SEARCH *

                *Filter: "Bursitis"

      

    Bursitis - Symptoms and causes - Mayo Clinic
    Bursitis (bur-SY-tis) is a painful condition that affects the small, fluid-filled sacs that cushion the bones, tendons and muscles near the joints. These sacs are called bursae (bur-SEE).

    Bursitis: Symptoms, Causes, and Treatment - WebMD
    Bursitis is inflammation or irritation of a bursa sac. Learn about the symptoms, causes, diagnostic methods and treatments to manage joint discomfort.

    Bursitis: Types, Treatment & Prevention - Cleveland Clinic
    Bursitis is painful swelling of a bursa, one of the fluid-filled sacs that cushion spaces between bones, muscles and other tissue inside your body.

    Bursitis - Wikipedia
    Bursitis is the inflammation of one or more bursae in the body. [1][2][3] Bursae are small sacs filled with lubricating synovial fluid that decrease friction at contact points between bones, skin, tendons, and muscle. [1]

    7 Bursitis Types, Symptoms, Causes, Treatment, and Cure
    Learn about bursitis, inflammation of a bursa, symptoms (pain), signs, types, causes, diagnosis, pain relief, home remedies, treatment, surgery, cure, and tips to prevent bursitis of the shoulder, elbow, wrist, knee, hip, foot, and ankle.

    Bursitis - Diagnosis and treatment - Mayo Clinic
    Try the following to relieve the pain of bursitis: Rest the affected area. Use ice to lessen swelling for the first 48 hours after symptoms start. Take a pain reliever you can get without a prescription. They include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve).

    Bursitis - NHS
    NHS information about bursitis, including symptoms, when to get help, treatments and prevention.

    Bursitis: Symptoms, Types, Treatment & More - Healthline
    Bursitis is an inflammation of the bursae, the fluid-filled sacs in your joints. Get the facts on types (like hip bursitis), causes, and more.

    Bursitis - symptoms and treatment | healthdirect
    Bursitis is when a bursa becomes inflamed. Bursae (or bursa in the singular) are fluid-filled 'cushions' that protect a tendon where it touches a bone. Symptoms of bursitis include pain, swelling, tenderness and limited joint movement. Bursitis can affect various joints like the shoulder, hip, knee and elbow.

    Bursitis - Johns Hopkins Medicine
    Pain, swelling, and tenderness near a joint are the most common signs of bursitis. Bursitis can be treated with rest and medicines to help with the inflammation.

     

     

     

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    Common Rheumatological Symptoms
    • Joint Pain (Arthralgia) — Persistent discomfort or soreness in one or more joints caused by inflammation, wear and tear, or underlying autoimmune responses.
    • Morning Stiffness — Reduced joint mobility and tightness upon waking, often lasting over 30 to 60 minutes in inflammatory conditions like rheumatoid arthritis.
    • Joint Swelling and Edema — Visible enlargement of affected joints resulting from fluid accumulation in the synovial membrane and inflamed surrounding tissue.
    • Localized Warmth and Redness — Elevated temperature and erythema skin discoloration surrounding inflamed joints due to increased blood flow from localized inflammation.
    • Systemic Fatigue — Overwhelming exhaustion and lack of energy caused by ongoing chronic inflammatory cytokine activity throughout the body.
    • Raynaud's Phenomenon — Temporary color changes in fingers or toes turning white, blue, and red in response to cold or stress due to vascular spasms.
    • Malar or Butterfly Rash — Red or purplish facial rash spanning across the bridge of the nose and cheeks, classically associated with systemic lupus erythematosus.

      

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    Milestones in Rheumatology History
    • c. 400 BC: Hippocratic Corpus Coining — Hippocrates uses the term "rheuma" to describe body humors flowing into joints, establishing the early classical concept of joint inflammation.
    • 1592: Formal Definition of Rheumatism — French physician Guillaume de Baillou introduces the modern term "rheumatism" to distinguish systemic acute arthritis from localized gout.
    • 1800: Clinical Description of Rheumatoid Arthritis — Augustin Jacob Landré-Beauvais publishes the first detailed clinical description separating rheumatoid arthritis from gout, calling it "asthenic gout."
    • 1859: Naming of Rheumatoid Arthritis — Sir Alfred Baring Garrod formally coins the term "rheumatoid arthritis" to clearly differentiate the inflammatory autoimmune condition from osteoarthritis and gout.
    • 1940: Discovery of the Rheumatoid Factor — Erik Waaler discovers autoantibodies in the blood of patients with rheumatoid arthritis, laying the groundwork for serological autoimmune diagnostics.
    • 1948: Introduction of Corticosteroid Therapy — Philip Hench and Edward Kendall demonstrate the dramatic anti-inflammatory effects of Compound E (cortisone) in treating rheumatoid arthritis, earning the Nobel Prize.
    • 1998: Emergence of Biologic DMARDs — The FDA approves the first TNF-alpha inhibitors, ushering in the modern era of targeted biologic therapies for autoimmune rheumatic diseases.
    Current Trends in Rheumatology Research
    • Chimeric Antigen Receptor (CAR) T-Cell Reset Therapy — Investigating engineered cellular therapies to achieve drug-free, durable clinical remissions by completely depleting pathogenic autoantibodies in severe refractory lupus and systemic sclerosis.
    • Selective TYK2 and Oral JAK Pathway Inhibition — Developing highly targeted, small-molecule oral inhibitors like deucravacitinib that disrupt specific cytokine signaling pathways while minimizing broader off-target side effects.
    • Targeted Pathogenic T-Cell and B-Cell Depletion — Evaluating novel biologics, such as rosnilimab and ianalumab, designed to selectively deplete overactive immune cell subpopulations involved in rheumatoid arthritis and Sjögren's disease.
    • Biomarker-Driven Precision Medicine — Utilizing pharmacogenomics and molecular biomarkers to predict individualized therapeutic responses and match systemic autoimmune conditions to specific biological mechanisms.
    • Subclinical Interception and Disease Prevention — Identifying seropositive individuals early using high-risk autoantibody profiles to initiate preventive targeted therapies before irreversible joint damage occurs.
    • Artificial Intelligence and Predictive Disease Modeling — Deploying machine learning algorithms across electronic health records and imaging modalities to forecast inflammatory flares and refine diagnostic accuracy.

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